新闻资讯

新闻中心
首页>新闻资讯>新闻中心

2022-12-20 19:21:47

Maleimide-PEG-DSPE 474922-22-0 磷脂-聚乙二醇-马来酰亚胺现货供应

一、产品描述


1、名称


中文:磷脂-聚乙二醇-马来酰亚胺


英文名:Maleimide-PEG-DSPE,DSPE-PEG-MAL


CAS:474922-22-0


2、Molecular weight: 20 k, PEG the optional customizable


3、Usage: use only for scientific research experiments


4、Solubility: soluble in water and buffer, chloroform, dichloromethane, DMF, DMSO, less soluble in alcohol, toluene. Insoluble in ethyl awake.


5、Appearance: white powder


6、Storage conditions: - 20 ℃ long-term preservation, feeling light, dry gas protection


7、Quality control: + 95%


8、Match current access: now, after taking into gas, sealing, sealing membrane twist tight cap into the valve bag, in a timely manner in the fridge.


二、产品结构式


474922-22-0

三、产品简介


DSPE-PEG-MAL是反应性磷脂PEG试剂之一,可以与巯基(硫醇,-SH)反应,DSPE(1,2-二硬脂酰基-sn-甘油3-磷酸乙醇胺)是一种高度疏水的饱和18C磷脂。另一方面,PEG接头(聚乙二醇)具有良好的亲水性和水溶性,马来酰亚胺官能的DSPE PEG对衍生自各种分子的巯基/硫醇基团具有出色的反应性,马来酰亚胺和硫醇之间的反应在中性pH下容易进行。


Maleic imide PEGDSPE liposome is liposome and other lipid nanoparticles on the surface of the antibodies, peptides or other ligand spatialization of one of the most commonly used the reactivity of phospholipids. Polyethylene glycol (PEG) of phospholipids have longer cycle time of blood and to the higher stability of the encapsulated drug, this product has high purity, excellent chemical reactivity and quantity of the various points of mercaptan reactive maleic imide phospholipids PEG products integrated products. The lipid PEG conjugated content have excellent amphiphilic, for the small molecule and the big drug preparation and transport advantages.Phospholipids PEG maleic imide (DSPE - PEG - Mal) can be used to modify proteins, peptides and other materials containing hydrophobic base or small molecules, maleic imide and hydrophobic base in PH6.5-7.5 it's easy to form stable sulfur wake key, (DSPE) conjugate polyethylene glycol (PEG) is a phospholipids and polyethylene glycol (PEG) combined with hydrophilic and hydrophobic. Polyethylene glycol lecithin liposome formation of high quality material, can be used for drug delivery, gene transfection and vaccine delivery, polyethylene glycol (peg), phospholipid encapsulated drugs can significantly improve the blood circulation time and stability, these materials can also be used for targeted drug delivery by modifying the ligands such as antibodies, peptides with the target surface.


四、相关产品


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:20000


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:10000


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:5000


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:3400


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:2000


DSPE-PEG-MAL,Maleimide-PEG-DSPE,MW:1000


DSPE-PEG-NHS,MW:20000


DSPE-PEG-NHS,MW:10000


DSPE-PEG-NHS,MW:5000


DSPE-PEG-NHS,MW:3400


DSPE-PEG-NHS,MW:2000


DSPE-PEG-NHS,MW:1000 

推荐新闻