产品名称：8-氨基-1,3,6-萘三磺酸二钠盐
英文名称：8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt
别名：8-氨基萘-1,3,6-三磺酸二钠盐；8-氨基萘-1,3,6-三磺酸 二钠盐；8-氨基-1,3,6-萘三磺酸二钠
英文别名：ANTS; Disodium 8-amino-1,3,6-naphthalenetrisulfonate; 1-Naphthylamine-3,6,8-trisulfonic Acid Disodium Salt; 8-Amino-1,3,6-naphthalenetrisulfonic Acid Disodium Salt; Amino H Acid Disodium Salt; Koch Acid Disodium Salt ；Amino H Acid Disodium Salt Hydrate；8-
应用：A fluorescent label
规格或纯度：98%
运输条件：常规运输
8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt is a fluorescent label for saccharides and glycoproteins, which is used in oligosaccharide sequencing and the study of membrane permeability and liposome lysis. ANTS has also been employed as a neuronal tracerA fluorescent label
8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt is a fluorescent label for saccharides and glycoproteins, which is used in oligosaccharide sequencing and the study of membrane permeability and liposome lysis. ANTS has also been employed as a neuronal tracerA fluorescent labelapplication：This molecular reagent is a polyanionic dye, which is often coupled with the cationic quencher DPX (X1525) for membrane fusion or permeability assays , including complement-mediated immune lysis. The fluorescence of ANTS has been shown to be effectively quenched by Thallium and Cesium ions. Utilized as a neuronal tracer. ANTS has a relatively high Stokes shift in water , which sufficiently separates its emission from the majority of the autofluorescence of biological samples. D2O increased the fluorescence quantum yield of ANTS four-fold, which has been demonstrated to be useful in the determination of water permeability in red blood cell ghosts and kidney collecting tubes . The reducing end of carbohydrates reacts with the primary amino group of the ANTS molecule, forming a Schiff base, which can then be reduced by sodium cyanoborohydride to a secondary amine. This reductive amination reaction is acid catalyzed, so the pH of the reaction solution can alter the kinetics and the degree of derivatization of the carbohydrate by ANTS. It is important to note this reaction is capable of proceeding at a neutral pH, which is favorable for the integrity of the sialic acid bonds in the oligosaccharide because they are sensitive to acid hydrolysis. Such labeling of carbohydrates with ANTS allows for complex mixtures to be separated via capillary electrophoresis .Fluorescent label for saccharides and glycoproteins used for oligosaccharide sequencing.
CAS编号：5398-34-5
敏感性：对湿度和光线敏感
储存温度充氩
Reaxys-RN：3854839
MDL号：MFCD00070572
密度：1.974
分子量：427.34
分子式：C10H7NNa2O9S3
EC号：226-431-6
PubChem CID：24181074
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