产品名称：1-脱氧甲基鞘氨醇(m17：0)
英文名称：1-desoxymethylsphinganine (m17:0)
别名：1-desoxymethylsphinganine
英文别名：1-deoxymethylsphinganine(2R)-1-amino-2-hydroxy-heptadecane1-deoxyMe SA1-desoxyMeSa
规格或纯度：>99%
运输条件：超低温冰袋运输
生化机理
1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons.
description：1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA.application：1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1.
description：1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA.application：1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1.
CAS编号：1219484-98-6
储存温度-20°C储存
分子量：271.482
分子式：C17H37NO
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