产品名称：神经酰胺（脑）
英文名称：Ceramide (Brain, Porcine)
别名：C18神经酰胺； N-十八烷酰基-D-赤型-鞘氨醇; N-（十八烷酰基）-鞘氨醇4-烯
英文别名：Ceramide (Brain);C18 Ceramide;N-octadecanoyl-D-erythro-sphingosine;N-(octadecanoyl)-sphing-4-enine
规格或纯度：99%
运输条件：超低温冰袋运输
生化机理
Ceramides are signalling molecules which play a key role in cellular events. Ceramides promote β-amyloid synthesis and induce neuronal death. Ceramide levels are associated with pathogenesis of many disease states. Impairment of ceramide metabolism is implicated in Parkinson′s and Alzheimer′s disease. High levels of ceramide is also associated with depression
Ceramides comprise sphingoid base attached to fatty acyl chain by an amide bond. They vary in length, saturation and hydroxylation of the fatty acid chain and sphingoid base. Ceramides are synthesized by sphingomyelinase in salvage and de novo synthesis pathway. In brain, ceramide synthases mediate the synthesis of ceramidesCeramide (Brain) has been used as a lipid standard· in ultra performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS)· in liquid chromatography with a hydrophilic interaction column· in liposome preparation to test it effect on human α-synuclein aggregation
CAS编号：497156-25-9

储存温度-20°C储存
分子量：565.954
分子式：C36H71NO3
PubChem CID：5283565

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