产品名称：Arimoclomol maleate
英文名称：Arimoclomol-d10 Maleic Acid
英文别名：N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidoyl Chloride 1-Oxide (2Z)-2-Butenedioate-d10
规格或纯度：98%
运输条件：超低温冰袋运输
生化机理：Arimoclomol is an orally available, CNS-penetrant coinducer of heat shock proteins (HSPs), notably HSP70, that exhibits in vivo efficay in disease models of diabetes, Gaucher disease (GD), sporadic inclusion body myositis (sIBM), and neurological disorders, including amyotrophic lateral sclerosis (ALS) and Niemann-Pick disease type C1 (NPC1). Note: arimoclomol maleate and citrate salt forms are known as BRX-220 and BRX-345, respectively.
产品介绍Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。Arimoclomol 通过增强 Hsp 表达来保护运动神经元，从而通过泛素-蛋白酶体系统直接影响蛋白质聚集及清除错误折叠和装配的蛋白
CAS编号：289893-26-1
敏感性：对湿度敏感
储存温度-20°C
储存分子量：429.85
分子式：C18H24ClN3O7Smiles
C1CCN(CC1)C[C@H](CON=C(C2=C[N+](=CC=C2)[O-])Cl)O.C(=CC(=O)O)C(=O)O
货号：Delta-72941795

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