产品名称：硫氟素 623
英文名称：ThioFluor 623
英文别名：Fluorescent Thiol Probe
规格或纯度：≥98%
运输条件：超低温冰袋运输
硫氟素 623在暴露于硫醇时会做出响应，荧光强度最多增加120倍。该反应对硫醇具有选择性，并在水性介质中发生。在不存在硫醇的情况下，探针基本上是无荧光的。硫醇引起探针的裂解，产生最大吸收波长为563 nm，发射波长为623 nm的荧光团。响应硫醇而生成的裂解产物的荧光量子产率在更多粘性介质中增加，表明在生物系统中具有理想的性能，并适用于单分子或2光子传感方案。硫氟素 623具有细胞渗透性，可与细胞内硫醇选择性反应。
Thiofluor 623 responds upon exposure to thiols with an increase in fluorescence intensity of up to 120-fold. The response is selective for thiols and occurs in aqueous media. In the absence of thiols, the probe is essentially non-fluorescent; thiols cause cleavage of the probe, making a fluorophore with an absorption maximum of 563 nm and emission at 623 nm. The fluorescence quantum yield of the cleaved product, generated in response to thiols, increases in more viscous media, suggesting ideal performance in biological systems and applicability to single-molecule or 2-photon sensing schemes. The thiofluor 623 is cell-permeable and reacts selectively with intracellular thiols.
CAS编号：1004324-99-5
溶解性：Soluble in ethanol, DMSO (~20 mg/ml), and DMF (~20 mg/ml).
储存温度-20°C储存
分子量：678.67
分子式：C₃₁H₃₀N₆O₁₀S
Smiles：COCCOCCOCCN(c1ccc(cc1)\\\\C=C/C1=C(CN)C(=C(CN)CN)OC1(C)C)S(=O)(=O)c1ccc(cc1[N](=O)O)[N](=O)O
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