DSP Crosslinker,CAS:57757-57-0,双端活性酯中间双硫键交联剂
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产品别名:
DSP Crosslinker,CAS:57757-57-0,双端活性酯中间双硫键交联剂
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发布时间:
2023-12-04 12:23:12
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产品规格:
100mg,500mg,可根据需求定制。大包装产品请咨询客服。
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产品纯度:
≥95%
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产品品牌:
德尔塔生物
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产品货期:
现货下单后48小时内发货,定制产品4-8周。
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运输条件:
顺丰常规运输
DSP Crosslinker,CAS:57757-57-0,双端活性酯中间双硫键交联剂
DSP crosslinker (DTSP; Dithiobis[succinimidyl propionate]; Lomant's Reagent) is a homobifunctional and cleavable crosslinker that is cell membrane permeable. DSP crosslinker has amine-reactive N-hydroxysuccinimide (NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm, and DSP cross links occur via these NHS esters. DSP crosslinking reagent contains a reducible disulfide (thiol) bond in the spacer arm that make it a good choice for various applications. The disulfide bond may be reduced with TCEP-HCl or DTT to reverse the crosslinked proteins.
A deuterated analog of DSP is available for mass spec studies. Use &uot;light&uot; DSP-d0non-deuterated protein crosslinking reagent in bination with the &uot;heavy&uot;, deuterated analog (DSP-d8) for mass spec experiments.
DSP crosslinker must be dissolved in an organic solvent, such as DMSO or DMF, then added to an aueous crosslinking reaction. DSP is soluble in DMF, DMSO, acetone, and chloroform (up to 50mg/ml). DSP crosslinking reagent can be used to crosslink intracellular proteins and is often used for crosslinking in immunoprecipitation (IP), Co-IP and ChIP assays. If extracellular crosslinking is desired, then DTSSP crosslinker, the water soluble analog of DSP can be used.
Some precipitation of DSP crosslinking reagent can occur when diluting DMSO-dissolved DSP crosslinker in PBS. In order to minimize DSP precipitation when DMSO-dissolved DSP stock is added to PBS, gentle vortexing the PBS solution while dropwise adding the DMSO stock solution may help. Gentle warming of the reaction solution may also help minimize precipitation. If a precipitate is observed, then the protein and DSP crosslinker concentrations should be decreased. Alternatively, DMSO concentration may be increased up to 20% of the final concentration in the reaction solution.
Molecular Weight: 404.42
Spacer Length: 12.0 Å
CAS Number:57757-57-0
Alternative names: 3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester); Di(N-succinimidyl) 3,3′-dithiodipropionate; Dithiobis-succinimidyl propionate; Dithio-bis-succinimidyl propionate; Dithiobis(succinimidyl propionate); Lomant's Reagent; DSP cross-linker; DTSP crosslinker; DSP-d0
structure:
DSP Crosslinker,CAS:57757-57-0,双端活性酯中间双硫键交联剂
西安德尔塔生物科技有限公司是国内ling命科学和生物技术领域试剂供应商,从成立初期就致力于为生命科学和生物技术领域提供优质产品和技术服务,力求将的产品和服务奉献给我们的客户。目前主要产品有:合成磷脂、血清、高分子聚乙二醇衍生物、嵌段共聚物、磁性纳米颗粒、纳米金及纳米金棒、近红外荧光染料、活性荧光染料、荧光标记的葡聚糖BSA和链霉亲和素、蛋白交联剂、小分子PEG衍生物、点击化学产品、树枝状聚合物、环糊精衍生物、热门肿瘤原料药、大环配体类、荧光量子点、透明质酸衍生物、石墨烯或氧化石墨烯、碳纳米管、富勒烯等等,可以满足从毫克级到公斤级的定制需求。我们非常乐于倾听您的需求,并一如既往地继续为您提供优质的产品和服务。
公司:西安德尔塔生物科技有限公司
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供应美国双功能交联剂(SMCC,Sulfo-SANPAH,PDPH,LC-SPDP,ANB-NOS)
我公司提供美国Proteochem交联剂产品,其中包括SMCC,LC-SPDP,BS3,Sulfo-EGS,NHS-Biotin,Biotin-HPDP,Sulfo-NHS-Acetate,NHS-SS-Biotin等等产品试剂。
产品列表:
SMCC,CAS:64987-85-5
Sulfo-SMCC,CAS:92921-24-9
Sulfo-SANPAH,CAS:102568-43-4
SMPH
PDPH
Sulfo-MBS
LC-SPDP
Sulfo-LC-SPDP
MBS,CAS:526-38-3
SPDP,CAS:68181-17-9
SIA,CAS:39028-27-8
SBA,CAS:42014-51-7
SMPB,CAS:798-55-8
BMPS,CAS:55750-62-4
EMCS,CAS:55750-63-5
GMBS,CAS:80307-12-6
ANB-NOS,CAS:60117-35-3
BS3,CAS:82436-77-9
DSS,CAS:68528-80-3
DSG,CAS:79642-50-5
DSP,CAS:57757-57-0
DTSSP,CAS:81069-02-5
Sulfo-EGS,CAS:167410-92-6
EGS,CAS:70539-42-3
DST,CAS:62069-75-4
Sulfo-NHS,CAS:106627-54-7
Sulfo-NHS-Acetate,CAS:152305-87-8
Sulfo-NHS-Biotin,CAS:119616-38-5
NHS-Biotin,CAS:35013-72-0
Sulfo-NHS-LC-Biotin,CAS:127062-22-0
NHS-LC-Biotin,CAS:72040-63-2
Sulfo-NHS-SS-Biotin,CAS:325143-98-4
NHS-SS-Biotin,CAS:142439-92-7
Biotin Hydrazide,CAS:66640--6
Biotin-HPDP,CAS:129179-83-5
Iodoacetyl-LC-Biotin,CAS:93285-75-7
如果有需要Proteochem公司的产品,请。
生产商:Proteochem
供应商:西安德尔塔生物科技有限公司 :-
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